NEET BIOLOGY

Detailed explanation-1: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C ) should exist.

Detailed explanation-2: -Chargaff rule: The rule that in DNA there is always equality in quantity between the bases A and T and between the bases G and C. (A is adenine, T is thymine, G is guanine, and C is cytosine.) Named for the great Austrian-American biochemist Erwin Chargaff (1905-2002) at Columbia University who discovered this rule.

Detailed explanation-3: -Chargaff’s rule states that the concentration of Adenine (A) always equal to the concentration of thymine and concentration of guanine always equal to the concentration of cytosine i.e the amount of purine is always equal to the amount of pyrimidine in a DNA molecule.

Detailed explanation-4: -Erwin Chargaff proposed the Chargaff’s rule. The rule played an essential role in discovering the double-helical structure of DNA. The rule states that in any double-stranded DNA, the ratios between Adenine and Thymine and Guanine and Cytosine are constant and equal.

Detailed explanation-5: -Abstract. Chargaff’ s second parity rule (PR2) states that complementary nucleotides are met with almost equal frequencies in single stranded DNA. This is indeed the case for all bacterial and eukaryotic genomes studied, although the genomic patterns may differ among genomes in terms of local deviations.