GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Leading Strand / Okazaki Fragments
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Lagging Strand / Okazaki Fragments
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Leading Strand / Topoisomerase
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Lagging Strand / dispersive replication
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Detailed explanation-1: -Okazaki fragments are short sections of DNA formed at the time of discontinuous synthesis of the lagging strand during replication of DNA. It is essential as it allows for the synthesis of both the daughter strands required for cell division.
Detailed explanation-2: -The strand with the Okazaki fragments is known as the lagging strand.
Detailed explanation-3: -The last deoxyribonucleotide is joined by a different enzyme, DNA ligase, which uses one ATP to join the Okazaki fragment into the growing lagging strand.
Detailed explanation-4: -The lagging strand is a single DNA strand that, during DNA replication, is replicated in the 5′ – 3′ direction (opposite direction to the replication fork). DNA is added to the lagging strand in discontinuous chunks called ‘okazaki fragments’.