NEET BIOLOGY

Detailed explanation-1: -The eukaryotic chromosome has multiple points of origin as this replication begins. The prokaryotic plasmid has one OriC. During replication, bubbles forms at multiple points on the eukaryotic chromosome, a replication fork is formed and replication occurs at each point of origin until the many bubbles merge.

Detailed explanation-2: -12.1 Eukaryotic Chromosomes Have Multiple Origins Eukaryotic chromosomes are much longer than bacterial ones and have multiple replication origins. Eukaryotic chromosomes are often very long and have numerous replication origins scattered along each chromosome. Replication is bi-directional as in bacteria.

Detailed explanation-3: -Prokaryotic chromosomes have one origin of replication, while eukaryotic chromosomes have multiple origins. This is because eukaryotic chromosomes are much larger, so multiple origins are needed to replicate the entire chromosome in a short amount of time.

Detailed explanation-4: -In contrast, eukaryotic genomes contain significantly more origins, ranging from 400 in yeast to 30, 000–50, 000 in humans (Cvetic and Walter 2005; Méchali 2010), because timely duplication of their larger linear chromosomes requires establishment of replication forks at multiple locations.

Detailed explanation-5: -Most bacterial chromosomes are circular and contain a single origin of chromosomal replication (oriC).