NEET BIOLOGY

GENETICS AND EVOLUTION

MOLECULAR BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What enzyme is responsible for laying down the RNA primers during DNA Replication?
A
Helicase
B
RNA Primase
C
Ligase
D
There are no RNA primers during DNA Replication
Explanation: 

Detailed explanation-1: -Polymerase can then synthesize both the leading and lagging strands, acting to extend the RNA-DNA primers initially synthesized by the polymerase -primase complex.

Detailed explanation-2: -RNA primase is the enzyme that builds an RNA primer on the DNA strands. In the second phase of DNA replication RNA primase builds an RNA primer on both the leading strand and lagging strand. This primer acts as a signal for DNA polymerase to come and add complementary base pairs to form the daughter strands of DNA.

Detailed explanation-3: -Primase synthesizes RNA primers complementary to the DNA strand. DNA polymerase III extends the primers, adding on to the 3’ end, to make the bulk of the new DNA. RNA primers are removed and replaced with DNA by DNA polymerase I. The gaps between DNA fragments are sealed by DNA ligase.

Detailed explanation-4: -RNA primase attaches a short RNA molecule called a primer to the DNA sequence, which is removed upon the completion of DNA replication. Another enzyme involved in gene expression is called RNA polymerase, which uses template DNA strands to form RNA molecules.

Detailed explanation-5: -DNA primases are enzymes whose continual activity is required at the DNA replication fork. They catalyze the synthesis of short RNA molecules used as primers for DNA polymerases.

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