GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Chromatin is loosely packed, while chromosomes are tightly packed.
|
|
|
Chromatin is tightly packed, while chromosomes are tightly packed.
|
|
|
Either A or B
|
|
|
None of the above
|
Detailed explanation-1: -The major difference between chromatin and chromosomes is that chromatin is composed of DNA and histones that are packed into a fiber whereas a chromosome is a single-stranded form of condensed chromatin. The chromosome structure is based on the fine fiber of chromatin.
Detailed explanation-2: -During interphase (1), chromatin is in its least condensed state and appears loosely distributed throughout the nucleus. Chromatin condensation begins during prophase (2) and chromosomes become visible. Chromosomes remain condensed throughout the various stages of mitosis (2-5).
Detailed explanation-3: -The DNA is packaged by special proteins called histones to form chromatin. The chromatin further condenses to form chromosomes. This means chromatin is a lower order of DNA organization, whereas chromosomes are a higher order of DNA organization.
Detailed explanation-4: -Heterochromatin is very tightly packed and condensed. The formation of heterochromatin involves modifications to histones and the recruitment and spreading of silencing complexes, which cause changes to the structure of chromatin.
Detailed explanation-5: -Loosely packed and lightly stained region of chromatin is called as euchromatin. Densely packed and dark stained region of chromatin is called as heterochromatin. A typical nucleosome contains 200 bp of DNA helix.