GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Chargaff’s Rule (C=A & T=G)
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Avery’s Rule (A=G & C=T
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Griffiths Rule (T=C & G=A)
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Chargaff’s Rule (A=T & G=C)
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Detailed explanation-1: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C ) should exist.
Detailed explanation-2: -Chargaff rule: The rule that in DNA there is always equality in quantity between the bases A and T and between the bases G and C. (A is adenine, T is thymine, G is guanine, and C is cytosine.) Named for the great Austrian-American biochemist Erwin Chargaff (1905-2002) at Columbia University who discovered this rule.
Detailed explanation-3: -Abstract. Chargaff’ s second parity rule (PR2) states that complementary nucleotides are met with almost equal frequencies in single stranded DNA. This is indeed the case for all bacterial and eukaryotic genomes studied, although the genomic patterns may differ among genomes in terms of local deviations.
Detailed explanation-4: -a. The amount of adenine, thymine, guanine, and cytosine varies from species to species and are not found in equal quantities. They do not vary between individuals of the same species and can be used to identify different species.