GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which enzyme is responsible for maintaining telomeres?
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Hexokinase
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Telomerase
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Topoisomerase
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Helicase
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Explanation:
Detailed explanation-1: -Telomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. Telomerase activity is exhibited in gametes and stem and tumor cells.
Detailed explanation-2: -Telomerase is an RNA-dependent DNA polymerase, meaning an enzyme that can make DNA using RNA as a template.
Detailed explanation-3: -The core enzyme consists of catalytic reverse transcriptase subunit TERT (Telomerase Reverse Transcriptase) and RNA subunit TER (Telomerase RNA), a short specific region of which serves as a template for synthesis of the telomeric repeats.
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