GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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single-stranded binding proteins
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helicase
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origin of replication
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ligase
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Detailed explanation-1: -Ligase is not involved in replication fork formation. The replication fork starts at origin of replication, then helicase unwinds the double helix structure to open up the replication fork.
Detailed explanation-2: -ligase is not involved during the formation of the replication fork.
Detailed explanation-3: -3: A replication fork is formed by the opening of the origin of replication, and helicase separates the DNA strands. An RNA primer is synthesized, and is elongated by the DNA polymerase. On the leading strand, DNA is synthesized continuously, whereas on the lagging strand, DNA is synthesized in short stretches.
Detailed explanation-4: -Final answer: DNA Ligase is not involved during DNA replication on the template with polarity 3’ → 5’.
Detailed explanation-5: -origin of replication d. ligase. As helicase is involved in the merging of the Okazaki fragments, it is not a component involved in the development of the replication fork.