GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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a deletion of three nucleotides near the middle of a gene
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a single nucleotide deletion in the middle of an intron
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a single nucleotide insertion downstream of, and close to, the start of the coding sequence
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a nucleotide-pair substitution
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Detailed explanation-1: -So, the correct option is ‘A single base insertion near the start of the coding sequence’.
Detailed explanation-2: -So, the correct option is ‘A missense substitution’
Detailed explanation-3: -The answer is A, frameshift mutation. Therefore, multiple amino acids in a protein change.
Detailed explanation-4: -Silent mutations are least likely to affect protein function. Missense mutations are often difficult to predict.
Detailed explanation-5: -Answer and Explanation: The type of mutation that is likely to have the greatest effect on a protein is B. Nonsense mutation. This is because a nonsense mutation creates a premature stop codon, leading to an incomplete formation of a protein, severely affecting protein structure and function.