NEET BIOLOGY

Detailed explanation-1: -The experiment done by Meselson and Stahl demonstrated that DNA replicated semi-conservatively, meaning that each strand in a DNA molecule serves as a template for synthesis of a new, complementary strand.

Detailed explanation-2: -The semiconservative mode of DNA replication was originally documented through the classic density labeling experiments of Matthew Meselson and Franklin W. Stahl, as communicated to PNAS by Max Delbrück in May 1958.

Detailed explanation-3: -Meselson and Stahl Experiment was an experimental proof for semiconservative DNA replication. In 1958, Matthew Meselson and Franklin Stahl conducted an experiment on E. coli which divides in 20 minutes, to study the replication of DNA.

Detailed explanation-4: -That left the scientists with only two options: either DNA replicated semiconservatively, as Watson and Crick had predicted, or it replicated dispersively. To differentiate between the two, Meselson and Stahl had to let the cells divide again and then sample the DNA after a second round of replication.

Detailed explanation-5: -In each new DNA molecule, one strand is old (original) while the other is newly formed. Hence, Watson and Crick described this method as semiconservative replication. Meselson and Stahl conducted experiments on E. coli to prove that DNA replication is semi conservative.