GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Heterocyclic nitrogenous bases
|
|
|
Chargaff’s rule
|
|
|
Complementary base pairing
|
|
|
5’ phosphoryl and 3’ hydroxyl ends
|
Detailed explanation-1: -Final Answer: Chargaff’s rules are not applicable to RNA.
Detailed explanation-2: -Chargaff’s rules are applicable only for double stranded DNA molecule. These are not applicable for single stranded DNA or RNA molecules.
Detailed explanation-3: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C ) should exist.
Detailed explanation-4: -Chargaff’s rules state that DNA from any cell of all organisms should have a 1:1 ratio of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine.
Detailed explanation-5: -A hydrogen bond binds guanine with cytosine and uracil with adenine. They are known as complementary base pairs. In RNA, a 2’ hydroxyl end is present and in DNA, a 3’ hydroxyl end is present. So, 5’ phosphoryl and 3’ hydroxyl do not belong to RNA.