GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Meselson & Stahl
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Hershey & Chase
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Watson & Crick
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Franklin & Watkins
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Detailed explanation-1: -Hershey and Chase concluded that protein was not genetic material, and that DNA was genetic material. Unlike Avery’s experiments on bacterial transformations, the Hershey-Chase experiments were more widely and immediately accepted among scientists.
Detailed explanation-2: -Hershey and Chase concluded that DNA, not protein, was the genetic material. They determined that a protective protein coat was formed around the bacteriophage, but that the internal DNA is what conferred its ability to produce progeny inside a bacterium.
Detailed explanation-3: -Alfred Hershey and Martha Chase showed that only the DNA of a virus needs to enter a bacterium to infect it. Their experiment provided strong support for the idea that genes are made of DNA. They firmly restated the conclusion that Avery, et al. had more tentatively proposed in 1944.
Detailed explanation-4: -Solution : Generally proteins contain sulphur but not phosphorous and nucleic acid (DNA) contains phosphorous but not sulphur. Hence Hershey-Chase used radioactive isotopes of sulphur S) and phosphorus (P) to keep separate track of viral protein and nucleic acid in culture medium.