NEET BIOLOGY

Detailed explanation-1: -When the plasma albumin level falls due to liver disease the colloid osmotic pressure of the blood is also reduced. Albumin produces the largest fraction of colloid osmotic pressure. Insufficient albumin allows fluid to move across vessel walls and into the interstitial spaces, causing generalized edema.

Detailed explanation-2: -A decrease in the albumin level was found to be the primary risk factor for an abnormal decline in the kidney function. More importantly, our study suggests that even when levels were still within the normal range, those with albumin levels of ≤4.6 g/dL had a risk of a decline in the kidney function.

Detailed explanation-3: -Decreased intravascular osmotic pressure most commonly results from decreased concentrations of plasma proteins, particularly albumin. Hypoalbuminemia reduces the intravascular colloidal osmotic pressure, resulting in increased fluid filtration and decreased absorption and culminating in edema.

Detailed explanation-4: -Albumin, the main protein produced in the liver, has numerous functions in the body, the most important of which is maintaining intravascular colloid osmotic pressure (COP). COP helps fluid stay within the vasculature instead of leaking into tissue.

Detailed explanation-5: -Albumin helps to balance osmotic concentration in body cells and tissues by keeping fluid in the bloodstream and preventing leakage into other tissues in the body.