HUMAN PHYSIOLOGY
BODY FLUIDS AND CIRCULATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Conversion of Vit. K to prothrombin
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Conversion of Vit. K to prothrombin
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Conversion of thrombin to prothrombin
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None of the above
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Detailed explanation-1: -There are two main mechanisms for triggering the blood clotting, termed the tissue factor pathway and the contact pathway. Only one of these pathways (the tissue factor pathway) functions in normal hemostasis. Both pathways, however, are thought to contribute to thrombosis.
Detailed explanation-2: -Explanation: Fibrinogen is a glycoprotein, during tissue injury it is converted by thrombin to fibrin and subsequently to a fibrin based blood clot.
Detailed explanation-3: -1) Constriction of the blood vessel. 2) Formation of a temporary “platelet plug.” 3) Activation of the coagulation cascade.
Detailed explanation-4: -Causes of acquired blood clotting disorders include: Cancer (one of the most common causes). Some medications that treat cancer. Recent trauma or surgery. Central venous catheter placement.