NEET BIOLOGY

Detailed explanation-1: -Erythroblastosis foetalis also called the haemolytic disease of the newborn. It is a type of anaemia in which the red blood cells (erythrocytes) of a fetus are destroyed in a maternal immune reaction resulting from a blood group incompatibility between the fetus and its mother.

Detailed explanation-2: -Hemolytic disease of the fetus and newborn (HDFN) is also known as alloimmune HDFN or erythroblastosis fetalis. It is caused by the destruction of neonatal red blood cells by maternal immunoglobulin G (IgG) antibodies.

Detailed explanation-3: -Erythroblastosis fetalis refers to life-threatening disease of a fetus or a new born infant in which the immune system of the mother produces antibodies against the red blood cells of the infant resulting in the destruction of the red blood cells of the fetus.

Detailed explanation-4: -(a) Erythroblastosis fetalis disease is related to it. (b) No antibodies develop in plasma in response to transfusion of Rh antigen.

Detailed explanation-5: -Erythroblastosis fetalis can be prevented by giving the mother anti Rh antibodies. These antibodies attach to the Rh antigens now circulating in the mother’s bloodstream and prevent her own immune cells from recognising the antigen.