HUMAN PHYSIOLOGY
BREATHING AND RESPIRATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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True; Pyruvate is transported into the cytoplasm then combined with a 4C molecule
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True; Pyruvate is transported into the mitochondria then combined with a 4C molecule
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False; Pyruvate must undergo Pyruvate Oxidation before entering the cytoplasm and being used
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False; the oxidized form of Pyruvate is combined with 4C molecule in mitochondria
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Detailed explanation-1: -Pyruvate is a biological molecule and product of glucose metabolism that reacts with adenosine triphosphate and carbon dioxide, converting it into acetyl-CoA and adenosine diphosphate (ADP) at the beginning of the TCA cycle. It is often included in the introductory or preliminary step of the cycle.
Detailed explanation-2: -In order to enter the Kreb’s Cycle pyruvate must first be converted into Acetyl-CoA by pyruvate dehydrogenase complex found in the mitochondria.
Detailed explanation-3: -No; enters by the formation of acetyl coenzyme A.
Detailed explanation-4: -Pyruvate metabolic pathways Pyruvate is then transported across the IMM by the MPC. It has also been suggested that the MPC transports ketone bodies across the IMM. In the mitochondrial matrix, pyruvate can be either oxidized into acetyl-CoA by PDH or carboxylated to oxaloacetate (OAA) by PC.