NEET BIOLOGY

HUMAN PHYSIOLOGY

BREATHING AND RESPIRATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What defines the essential role of NADH in metabolic pathways?
A
It allows molecules to be oxidized by removing there electron
B
It transfers its electron to the ETC so it can be used in chemiosmosis
C
It gives molecules energy by oxidizing them
D
It gives molecules energy by reducing them
Explanation: 

Detailed explanation-1: -The role of NADH in metabolism is to act as an electron carrier, shuttling electrons from glycolysis and the citric acid cycle to the electron transport chain.

Detailed explanation-2: -NADH is the electron donor in this system. It initiates the electron transport chain by donating electrons to NADH dehydrogenase (blue). NADH donates two electrons to NADH dehydrogenase. At the same time, the complex also pumps two protons from the matrix space of the mitochondria into the intermembrane space.

Detailed explanation-3: -During chemiosmosis, electron carriers like NADH and FADH donate electrons to the electron transport chain. The electrons cause conformation changes in the shapes of the proteins to pump H+ across a selectively permeable cell membrane.

Detailed explanation-4: -To perform its role as an electron carrier, NAD must revert back and forth between the two forms. When NAD+ takes an electron from glucose, it becomes NADH, the reduced form of the molecule. NADH transports this electron to mitochondria where the cell can take the energy that is stored in the electron.

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