NEET BIOLOGY

Detailed explanation-1: -Pepsin is a stomach enzyme that serves to digest proteins found in ingested food. Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin.

Detailed explanation-2: -Abstract. Pepsin is an aspartic protease that acts in food digestion in the mammal stomach. An optimal pH of around 2 allows pepsin to operate in its natural acidic environment, while at neutral pH the protein is denatured.

Detailed explanation-3: -For example, the enzyme pepsin (a protease enzyme) is most active at an acidic pH, whereas the enzyme trypsin (another protease enzyme) performs best at a slightly alkaline pH.

Detailed explanation-4: -Pepsin’s optimum pH is 1.8, which is quite acidic. Because the carboxylic acid group on the amino acid in the enzyme’s active site must be in its protonated state, meaning bonded to a hydrogen atom, pepsin works best at pH 1.8 .

Detailed explanation-5: -Answer and Explanation: Pepsin is an activated form of the zymogen pepsinogen secreted by the chief cells of the stomach. It has an acidic optimum pH of 1.5 where it efficiently cleaves proteins into shorter peptide chains.