HUMAN PHYSIOLOGY
DIGESTION AND ABSORPTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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GLUT-1-glucose uptake is independent of insulin
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GLUT-2-located in liver and kidney
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GLUT-3-located in brain kidney and placenta
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GLUT-4-function as insulin stimulated glucose uptake
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GLUT-5-red blood cell, brain and kidney
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Detailed explanation-1: -The main glucose transporters in the brain are Glut1 and Glut3. Of these, Glut1 exists in two isoforms of different molecular weights.
Detailed explanation-2: -GLUT5 (SLC2A5) is a high-affinity fructose transporter primarily expressed at the apical surface of intestinal epithelial cells but also at lower levels in testis, kidney, brain, skeletal muscle and white adipose tissue (WAT)15.
Detailed explanation-3: -GLUT5, an apically expressed transmembrane protein, facilitates fructose absorption by moving the sugar down a chemical gradient. Its cDNA has been cloned from the human, rabbit, rat, and mouse intestine.
Detailed explanation-4: -There are five known Class III glucose facilitative transporters, namely, GLUT6, GLUT8, GLUT10, GLUT12 and GLUT13 (HMIT).