HUMAN PHYSIOLOGY
DIGESTION AND ABSORPTION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Hydrolysis of TG is initiated by pancreatic lipase in mouth and stomach
|
|
|
Short chain FAs released are absorbed directly into bloodstream and need to be packaged into chylomicron
|
|
|
Effective digestion due to presence of bile salts, pancreatic lipase and colipase
|
|
|
Micelles are important for the transportation of lipids
|
|
|
Bile salts helps in emulsification of lipids
|
Detailed explanation-1: -Emulsification: In the small intestine lipids are emulsified by bile salts. Bile salts (bile salts = conjugation of bile acids with taurine or glycine) are polar and water soluble and function as detergents whereby they emulsifies larger fats into smaller droplets.
Detailed explanation-2: -Bile salts helps in emulsification of fats, i.e., breaking down of the large fat droplets into very small micelles. Bile also activates lipase enzymes, which digests fats.
Detailed explanation-3: -Emulsification is possible due to the amphipathic property of bile salts [1]. The hydrophilic portion of the bile salts surrounds the lipid, forcing the lipid to disperse as the negative charges repel each other. Bile salts also allow the products of lipid digestion to be transported as micelles.
Detailed explanation-4: -Bile salts (BS) are bio-surfactants present in the gastrointestinal tract (GIT) that play a crucial role in the digestion and absorption of nutrients.
Detailed explanation-5: -Because of their unusual chemical structure, bile salts (BS) play a fundamental role in intestinal lipid digestion and transport. BS have a planar arrangement of hydrophobic and hydrophilic moieties, which enables the BS molecules to form peculiar self-assembled structures in aqueous solutions.