NEET BIOLOGY

Detailed explanation-1: -Gastric acid secretion is under nervous and hormonal control. Gastrin, the major circulating stimulus of acid secretion, probably does not stimulate the parietal cells directly but acts to mobilize histamine from the ECL cells in the oxyntic mucosa. Histamine stimulates the parietal cells to secrete HCl.

Detailed explanation-2: -The medulla oblongata controls gastric secretion both by the parasympathetic branch of the nervous system and the endocrine system.

Detailed explanation-3: -During meal ingestion, the main hormone responsible for stimulating acid secretion is gastrin, which acts primarily by releasing histamine from enterochromaffin-like cells.

Detailed explanation-4: -The process is controlled by a complex system of endocrine cells and neurons. Gastrin is the main hormone regulating gastric acid secretion, and is phylogenetically older than gastric acidity [8].