NEET BIOLOGY

Detailed explanation-1: -Embedded in the end plate are thousands of receptors, which are long protein molecules that form channels through the membrane. Upon stimulation by a nerve impulse, the terminal releases the chemical neurotransmitter acetylcholine from synaptic vesicles.

Detailed explanation-2: -The motor end plate is also known as the neuromuscular junction. The neuromuscular junction is the synaptic connection between the terminal part of the axon of the motor neuron and a muscle (skeletal, smooth, and cardiac).

Detailed explanation-3: -End plate potentials (EPPs) are the voltages which cause depolarization of skeletal muscle fibers caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction. They are called “end plates” because the postsynaptic terminals of muscle fibers have a large, saucer-like appearance.

Detailed explanation-4: -The neuromuscular junction has three main parts: a presynaptic membrane, which is the membrane of an axon terminal; a postsynaptic membrane, which is the membrane of a skeletal muscle fiber and is also called a motor end-plate; and a synaptic cleft, which is the gap between the presynaptic and postsynaptic membrane.

Detailed explanation-5: -At the neuromuscular junction, the end-plate potential is generated by a conductance increase in the end-plate membrane. The end-plate depolarization brings the membrane potential toward the reversal potential, which diminishes the driving force for inward current flow.