HUMAN PHYSIOLOGY
LOCOMOTION AND MOVEMENT
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Detailed explanation-1: -Abstract. Troponin complex is a component of skeletal and cardiac muscle thin filaments . It consists of three subunits-troponin I, T, and C, and it plays a crucial role in muscle activity, connecting changes in intracellular Ca2+ concentration with generation of contraction.
Detailed explanation-2: -Troponin consists of three subunits: TnT, TnI, and TnC (7). TnT binds to tropomyosin and anchors the troponin complex on the thin filament. In the presence of actin, TnI inhibits myosin ATPase cycle at low Ca levels.
Detailed explanation-3: -The troponin complex is made up of three components8–10: the calcium binding subunit, troponin C (TnC); the inhibitory subunit, troponin I (TnI); and an elongated protein, troponin T (TnT), that binds both TnC and TnI and anchors the entire complex to tropomyosin.
Detailed explanation-4: -0–0.04 ng/ml. Above 0.40 ng/ml. Having a result between 0.04 and 0.39 ng/ml often indicates a problem with the heart. However, a very small number of healthy people have higher-than-average levels of troponin.
Detailed explanation-5: -Cardiac troponin (cTn) acts as a pivotal regulator of muscle contraction and relaxation and is composed of three distinct subunits (cTnC: a highly conserved Ca2+ binding subunit, cTnI: an actomyosin ATPase inhibitory subunit, and cTnT: a tropomyosin binding subunit).