NEET BIOLOGY

REPRODUCTION

HUMAN REPRODUCTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In humans, the oocyte is maintained in a state of meiotic arrest by secretion of
A
Granulosa cells
B
Zona pellucida
C
Cumulus oophorus
D
Theca
Explanation: 

Detailed explanation-1: -So, the correct answer is ‘Granulosa cells’.

Detailed explanation-2: -Granulosa cells supply nutrients and metabolites through gap junctions to oocytes and secrete paracrine signals to regulate oocytes. Oocytes regulate granulosa cell proliferation and differentiation and induce antrum formation via GDF9 and BMP15.

Detailed explanation-3: -Granulosa cells play a key role in the female reproductive system. They help you get and stay pregnant. Granulosa cells produce reproductive hormones and support ovarian follicles. These follicles are small sacs of fluid in your ovaries that contain eggs.

Detailed explanation-4: -The reason for halting egg at meiosis I during oogenesis is to decrease the number of chromosomes in the cell, making it haploid. When a female reaches adolescence, her primary oocytes undergo meiosis I, resulting in the formation of secondary oocytes.

Detailed explanation-5: -In female mammals, meiosis of oocytes starts before birth and sustains at the dictyate stage of meiotic prophase I before gonadotropins-induced ovulation happens. Once meiosis gets started, the oocytes undergo the leptotene, zygotene, and pachytene stages, and then arrest at the dictyate stage.

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