NEET BIOLOGY

Detailed explanation-1: -Fibroblasts produce the ECM’s structural proteins (e.g., fibrous collagen and elastin), adhesive proteins (e.g., laminin and fibronectin), and ground substance (e.g., glycosaminoglycans, such as hyaluronan and glycoproteins). However, fibroblasts also play various additional roles beyond ECM production.

Detailed explanation-2: -The most abundant cell in connective tissue proper is the fibroblast. Polysaccharides and proteins secreted by fibroblasts combine with extra-cellular fluids to produce a viscous ground substance that, with embedded fibrous proteins, forms the extra-cellular matrix.

Detailed explanation-3: -Fibroblasts seem to be the least specialized cells in the connective-tissue family. They are dispersed in connective tissue throughout the body, where they secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen, as discussed in Chapter 19.

Detailed explanation-4: -Connective tissue is made up of individual cells that are embedded in an extracellular matrix. The cells of connective tissue include fibroblast. The matrix is made up of ground substance and fibres such as collagen and elastic fibres which are secreted by the fibroblast cells.