BRAIN
CEREBRUM
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 Question 
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 Parkinson’s disease is indicated by 
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  Degeneration of neurons of the basal ganglia 
 
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  Damage to the corpus striatum 
 
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  Damage to the hippocampus 
 
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  Loss of neurons of the nucleus basalis 
 
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 Explanation: 
Detailed explanation-1: -Parkinson’s is the most notorious disease of the basal ganglia. Classic clinical symptoms include bradykinesia, resting tremor, postural instability, and shuffling gait. This disease is a result of neurodegeneration of the SNpc dopaminergic neurons.
Detailed explanation-2: -In Parkinson disease, nerve cells in part of the basal ganglia (called the substantia nigra) degenerate.
Detailed explanation-3: -Damage to the basal ganglia cells may cause problems controlling speech, movement, and posture. This combination of symptoms is called parkinsonism. A person with basal ganglia dysfunction may have trouble starting, stopping, or sustaining movement.
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