NEET PG DENTAL EXAM

Detailed explanation-1: -Nociceptors respond when a stimulus causes tissue damage, such as that resulting from cut strong mechanical pressure, extreme heat, etc. The damage of tissue results in a release of a variety of substances from lysed cells as well as from new substances synthesized at the site of the injury (Figure 6.5).

Detailed explanation-2: -The pain receptors are nociceptors. They are known to exist in muscle, joints, and skin. Each nociceptor has selective sensitivity to mechanical (muscle-fiber stretching), chemical (including lactic acid), and thermal stimuli.

Detailed explanation-3: -In short, there are three major classes of nociceptors in the skin: A mechanosensitive nociceptors, A mechanothermal nociceptors, and polymodal nociceptors, the latter being specifically associated with C fibers.