NEET PG DENTAL EXAM

BRAIN

CRANIAL NERVES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
These glial cells control the permeability of the blood brain barrier
A
Microglial cells
B
Astrocytes
C
Ependymal cells
D
Oligodendrocytes
Explanation: 

Detailed explanation-1: -Astrocytes are essential for the formation and maintenance of the BBB by providing secreted factors that lead to the adequate association between the cells of the BBB and the formation of strong tight junctions.

Detailed explanation-2: -Answer and Explanation: The neuroglial cell that helps to maintain the blood-brain barrier is C. astrocytes. Astrocytes are sometimes referred to as “star shaped” cells that cover the capillaries of the brain and form a net like structure that filters blood plasma as it leaves the capillaries and enters brain tissue.

Detailed explanation-3: -Astrocytes not only regulate blood flow, but also transfer mitochondria to neurons, and supply the building blocks of neurotransmitters, which fuel neuronal metabolism [2, 11, 57]. In addition, astrocytes can phagocytose synapses, alter neurotrophin secretion, and clear debris [14, 58].

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