NEET PG DENTAL EXAM

Detailed explanation-1: -This leads to a number of problems and is thought to affect part of the brain called the hypothalamus, which produces hormones and regulates growth and appetite. This may explain some of the typical features of Prader-Willi syndrome, such as delayed growth and persistent hunger.

Detailed explanation-2: -A key feature of Prader-Willi syndrome is a constant sense of hunger that usually begins at about 2 years of age. People with Prader-Willi syndrome want to eat constantly because they never feel full (hyperphagia), and they usually have trouble controlling their weight.

Detailed explanation-3: -This can lead to severe obesity if excessive eating isn’t managed. PWS typically also causes a delay in childhood milestones and puberty. Although rare, life-threatening complications can occur and include respiratory illnesses, obesity-related cardiovascular problems, sleep apnea and diabetes.

Detailed explanation-4: -Prader–Willi syndrome (PWS) is characterized by a dysregulation of growth hormone (GH)/insulin-like growth factor I axis, as the consequence of a complex hypothalamic involvement.