NEET PG DENTAL EXAM

Detailed explanation-1: -In physiology, a refractory period is a period of time during which an organ or cell is incapable of repeating a particular action, or (more precisely) the amount of time it takes for an excitable membrane to be ready for a second stimulus once it returns to its resting state following an excitation.

Detailed explanation-2: -In excitable tissues the refractory period is a critical control mechanism preventing hyperactivity and undesirable tetani, by preventing subsequent stimuli eliciting action potentials and Ca2+ entry.

Detailed explanation-3: -The refractory period is the time after an action potential is generated, during which the excitable cell cannot produce another action potential. There are two subphases of this period, absolute and relative refractoriness. Absolute refractoriness overlaps the depolarization and around 2/3 of repolarization phase.