NEET PG DENTAL EXAM

Detailed explanation-1: -A frameshift mutation in a gene refers to the insertion or deletion of nucleotide bases in numbers that are not multiples of three. This is important because a cell reads a gene’s code in groups of three bases when making a protein.

Detailed explanation-2: -Crohn’s disease, cystic fibrosis, and certain types of cancer are due to frameshift mutations.

Detailed explanation-3: -Deletion frameshift mutation: When in the nucleic acid, one or more nucleotides are deleted, resulting in reading frameshift. Insertion frameshift mutation: When in the nucleic acid, one or more nucleotides are added, resulting in reading frameshift.