NEET PG DENTAL EXAM

Detailed explanation-1: -DNA replication occurs through the help of several enzymes. These enzymes “unzip” DNA molecules by breaking the hydrogen bonds that hold the two strands together. Each strand then serves as a template for a new complementary strand to be created.

Detailed explanation-2: -The initiation of DNA replication occurs in two steps. First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands.

Detailed explanation-3: -Therefore for replication to happen, the two strands need to be separated. This is done by the enzyme helicase which opens up the double helix for the replication process to begin.

Detailed explanation-4: -Proteins called single-strand binding proteins coat the separated strands of DNA near the replication fork, keeping them from coming back together into a double helix.