NEET PG DENTAL EXAM

Detailed explanation-1: -A sister chromatid refers to the identical copies (chromatids) formed by the DNA replication of a chromosome, with both copies joined together by a common centromere. In other words, a sister chromatid may also be said to be ‘one-half’ of the duplicated chromosome.

Detailed explanation-2: -Both the cells are genetically identical to the parent cell. In addition to this basic function, sister chromatids play an important role in maintaining the integrity of the genome by being involved in DNA repair. They are usually spatially close to each other, compared to the homologous chromosome pair.

Detailed explanation-3: -They are called sister chromatids because all the genes and to be specific all the alleles are exactly the same because they are identical copies (Figure 1). Sister Chromatids = Replicated Chromosomes Attached at the Centromere.

Detailed explanation-4: -Indeed, most studies assume that sister chromatids, being genetically identical, are also functionally identical and that segregation to daughter cells proceeds randomly.