NEET PG DENTAL EXAM

Detailed explanation-1: -Metaphase is a stage during the process of cell division (mitosis or meiosis). Normally, individual chromosomes are spread out in the cell nucleus. During metaphase, the nucleus dissolves and the cell’s chromosomes condense and move together, aligning in the center of the dividing cell.

Detailed explanation-2: -Chromosomes are evenly aligned at the metaphase plate. It is due to an equal but opposing physical pulling by spindle fibers, which originates from opposite poles of the cell.

Detailed explanation-3: -Spindle fibers align the chromosomes along the middle of the cell nucleus. This line is referred to as the metaphase plate. This organization helps to ensure that in the next phase, when the chromosomes are separated, each new nucleus will receive one copy of each chromosome.

Detailed explanation-4: -During mitosis, chromosomes are bound to microtubules emanating from both poles of the mitotic spindle via sister-kinetochores and aligned on the metaphase plate precisely in the middle of the spindle.