NEET PG DENTAL EXAM

EMBRYOLOGY

CHROMOSOMES AND CELL DIVISIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What would you call the failure of one or more pairs of homologous chromosomes or sister chromatids to separate normally during meiosis?
A
nondisjunction
B
anaphase I
C
nondiploidy
D
karyotype
Explanation: 

Detailed explanation-1: -Nondisjunction in meiosis II results from the failure of the sister chromatids to separate during anaphase II.

Detailed explanation-2: -Likewise, abnormal separation can occur in meiosis when homologous pairs fail to separate during anaphase I. This also results in daughter cells with different numbers of chromosomes. The phenomenon of unequal separation in meiosis is called nondisjunction.

Detailed explanation-3: -Nondisjunction in meiosis can result in pregnancy loss or birth of a child with an extra chromosome in all cells, whereas nondisjunction in mitosis will result in mosaicism with two or more cell lines. Aneuploidy may also result from anaphase lag.

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