NEET PG DENTAL EXAM

Detailed explanation-1: -b) Glucagon-insulin hormone is an antagonist to glucagon because it reacts opposite to the function of insulin. Insulin role is to maintain the glucose level in the blood stream whereas glucagon hormone is known for raising the concentration of glucose in blood.

Detailed explanation-2: -The glucagon-insulin antagonism was maximally expressed when glucagon was present at low physiological concentrations. At equimolar doses it was only in the concentration range around 0.1 nM that glucagon and insulin became powerful antagonists; at higher levels glucagon was the dominant hormone.

Detailed explanation-3: -The hormone glucagon plays a major role in the initiation and elevation of hyperglycemia in DM. Insulin and glucagon antagonize each other in the regulation of glucose level. In DM the blood plasma ratio of glucagon versus insulin levels in the blood plasma is higher than that observed in healthy controls.