NEET PG DENTAL EXAM

Detailed explanation-1: -CRH stimulates the anterior pituitary to release ACTH. ACTH acts on the adrenal cortex to release cortisol and androgens. The increase in cortisol provides a negative feedback system to decrease the amount of CRH released from the hypothalamus.

Detailed explanation-2: -Your anterior pituitary produces and releases (secretes) six main hormones: Adrenocorticotropic hormone (ACTH, or corticotropin): This hormone stimulates your adrenal glands (the glands on top of your kidneys) to produce cortisol and other hormones.

Detailed explanation-3: -ACTH primarily functions to regulate cortisol and androgen production. The ACTH released from the anterior pituitary acts on its target organ, the Adrenal gland, and stimulates the production of Glucocorticoids from the Zona Fasiculata and androgens from the Zona Reticularis.

Detailed explanation-4: -ACTH travels to the adrenal glands via the bloodstream (arrow). Cortisol from the adrenal then feeds back to the hypothalamus to shut down the cycle. Adrenocorticotropic hormone is made in the corticotroph cells of the anterior pituitary gland.