EMBRYOLOGY
NERVOUS SYSTEM
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
producing cerebrospinal fluid
|
|
|
creating the blood brain barrier
|
|
|
producing myelin sheath
|
|
|
destroying cancer cells
|
Detailed explanation-1: -Astrocytes are essential for the formation and maintenance of the BBB by providing secreted factors that lead to the adequate association between the cells of the BBB and the formation of strong tight junctions.
Detailed explanation-2: -The BBB is formed by microvascular endothelial cells lining the cerebral capillaries penetrating the brain and spinal cord of most mammals and other organisms with a well-developed CNS [3].
Detailed explanation-3: -Astrocytes not only regulate blood flow, but also transfer mitochondria to neurons, and supply the building blocks of neurotransmitters, which fuel neuronal metabolism [2, 11, 57]. In addition, astrocytes can phagocytose synapses, alter neurotrophin secretion, and clear debris [14, 58].