NEET PG DENTAL EXAM

Detailed explanation-1: -Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused mainly by lack of dopamine in the brain. Dopamine is a neurotransmitter involved in movement, motivation, memory, and other functions; its level is decreased in PD brain as a result of dopaminergic cell death.

Detailed explanation-2: -Low levels of dopamine may disrupt the nigrostriatal pathway and cause abnormal nerve firing patterns, which can result in movement problems. Evidence suggests that most people with PD lose 60–80% or more of dopamine-producing cells in the substantia nigra by the time they present symptoms.

Detailed explanation-3: -Parkinson’s disease is a brain disorder that causes unintended or uncontrollable movements, such as shaking, stiffness, and difficulty with balance and coordination. Symptoms usually begin gradually and worsen over time. As the disease progresses, people may have difficulty walking and talking.

Detailed explanation-4: -Parkinson’s disease is caused by a loss of nerve cells in the part of the brain called the substantia nigra. Nerve cells in this part of the brain are responsible for producing a chemical called dopamine.