NEET PG DENTAL EXAM

Detailed explanation-1: -Microglia are brain professional phagocytes mainly finalized to clearance of apoptotic or necrotic cells (Green et al., 2016) and removal of unfolded proteins such as amyloid beta (A) or neuromelanin.

Detailed explanation-2: -Microglia are resident macrophages of the central nervous system and significantly contribute to overall brain function by participating in phagocytosis during development, homeostasis, and diseased states.

Detailed explanation-3: -The brain resident microglia are the main macrophages engaged in phagocytosis in the early stage of demyelination, while in the late stage a number of infiltrated blood-borne macrophages contribute to axon debris clearance.