NEET PG DENTAL EXAM

Detailed explanation-1: -Sodium (Na+) and chloride (Cl−) ions are at high concentrations in the extracellular region, and low concentrations in the intracellular regions. These concentration gradients provide the potential energy to drive the formation of the membrane potential.

Detailed explanation-2: -The principal ions involved in an action potential are sodium and potassium cations; sodium ions enter the cell, and potassium ions leave, restoring equilibrium. Relatively few ions need to cross the membrane for the membrane voltage to change drastically.

Detailed explanation-3: -The dominant ion in setting the resting membrane potential is potassium. Potassium conductance accounts for approximately 20% of the resting membrane conductance in skeletal muscle and accounts for most of the resting conductance in neurons and nerve fibers.

Detailed explanation-4: -[3][4] The Na+K+-ATPase pump helps to maintain osmotic equilibrium and membrane potential in cells. The sodium and potassium move against the concentration gradients. The Na+ K+-ATPase pump maintains the gradient of a higher concentration of sodium extracellularly and a higher level of potassium intracellularly.