NEET PG DENTAL EXAM

Detailed explanation-1: -The cell responsible for bone resorption, or breakdown, is the osteoclast, which is found on bone surfaces, is multinucleated, and originates from monocytes and macrophages (two types of white blood cells) rather than from osteogenic cells.

Detailed explanation-2: -Osteoclasts are the cells that degrade bone to initiate normal bone remodeling and mediate bone loss in pathologic conditions by increasing their resorptive activity. They are derived from precursors in the myeloid/monocyte lineage that circulate in the blood after their formation in the bone marrow.

Detailed explanation-3: -The osteoclast: a multinucleated, hematopoietic-origin, bone-resorbing osteoimmune cell.

Detailed explanation-4: -Answer and Explanation: Osteoclasts are multinucleated cells that destroy bone. They are derived from as many as 50 monocytes that have fused together. On the side of the osteoclast that is closest to the bone surface is the ruffled border.