NEET PG DENTAL EXAM

HISTOLOGY

CONNECTIVE TISSUE

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

Fixed macrophages usually have a specific name depend on where it is located in the body, so where are the Kupffer cell locate in the body?

A	Bone
B	Epidermis
C	Lungs
D	Liver
E	Lymph nodes

Explanation:

Detailed explanation-1: -The Kupffer cell is located to the hepatic sinusoid and is therefore in close proximity to other cells in the sinusoid, including natural killer (NK) and natural killer T cells (NKT), as well as the liver sinusoidal endothelial cells (LSEC).

Detailed explanation-2: -Kupffer cells are macrophages that are fixed within the sinusoids of the liver. They are the body’s most abundant source of fixed macrophages.

Detailed explanation-3: -The primary function of the Kupffer cell is to remove foreign debris and particles that have come from the hepatic portal system when passing through the liver. It is possible for the Kupffer cells to take in large particles by phagocytosis and smaller particles via pinocytosis.

Detailed explanation-4: -Kupffer cells are involved in the defence against infections of the liver. Their major role in the host defence and the prognosis of liver infection is indicated by studies in experimental models of sepsis.

There is 1 question to complete.