NEET PG DENTAL EXAM

HISTOLOGY

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The matrix or GROUND SUBSTANCE of bone is primarily:
A
Collagen
B
Collagen and Cartilage
C
Calcium and Collagen
D
Cartilage
Explanation: 

Detailed explanation-1: -The organic matrix of bone is composed of collagen and non-collagenous organic materials. Collagen comprises about 90% of the organic bone matrix. Type I collagen is the most abundant form of intrinsic collagen found in the bone that is secreted by osteoblasts.

Detailed explanation-2: -Bone matrix (also known as osteoid) consists of about 33% organic matter (mostly Type I collagen) and 67% inorganic matter (calcium phosphate, mostly hydroxyapatite crystals). The osteoblasts occur as simple, epithelial-like layer at the developing bone surface.

Detailed explanation-3: -The ground substance of bone is mineralized, making the bone rigid and strong, but brittle. The ground substance of cartilage is not mineralized but is more like very firm Jello®, making cartilage stiff and incompressible but more flexible and resilient than bone.

Detailed explanation-4: -Bone matrix The hardness and rigidity of bone is due to the presence of mineral salt in the osteoid matrix, which is a crystalline complex of calcium and phosphate (hydroxyapatite).

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