HISTOLOGY
CONNECTIVE TISSUE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Fibroblast
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Mast cell
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Macrophages
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None of the above
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Detailed explanation-1: -A mast cell (also known as a mastocyte or a labrocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. Specifically, it is a type of granulocyte derived from the myeloid stem cell that is a part of the immune and neuroimmune systems.
Detailed explanation-2: -During allergic reactions, basophils release two enzymes, histamine and heparin.
Detailed explanation-3: -Mast cells play an important role in how the immune system responds to certain bacteria and parasites and they help control other types of immune responses. They contain chemicals such as histamine, heparin, cytokines, and growth factors.
Detailed explanation-4: -The IgE-primed mast cell releases granules and powerful chemical mediators, such as histamine, cytokines, granulocyte macrophage colony-stimulating factor (GM-CSF), leukotrienes, heparin, and many proteases into the environment. These chemical mediators cause the characteristic symptoms of allergy.