NEET PG DENTAL EXAM

HISTOLOGY

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
This cell is large and widely distributed. It is located near blood vessels involved with the immune response by releasing histamines and heparin
A
Fibroblast
B
Mast cell
C
Macrophages
D
None of the above
Explanation: 

Detailed explanation-1: -The function of basophils is similar to that of mast cells. Hence, both these cells comprise histamine, heparin and serotonin.

Detailed explanation-2: -During allergic reactions, basophils release two enzymes, histamine and heparin.

Detailed explanation-3: -Heparin, well known anticoagulant, can also modulate inflammatory and immunologic processes. Some investigators suggest that heparin inhibits mast cell degranulation. Mast cells play very important role in early phase of asthmatic reaction, releasing many proinflammatory mediators including histamine.

There is 1 question to complete.