NEET PG DENTAL EXAM

HISTOLOGY

DIGESTIVE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why doesn’t the stomach digest itself with hydrochloric acid?
A
It is lined with villi to protect the lining of the stomach
B
the lining is covered with mucus to protect itself
C
the stomach wall becomes immune to the strong acid over time
D
the stomach walls are made of very thick skeletal muscle.
Explanation: 

Detailed explanation-1: -The acidic gastric juice also kills bacteria. The mucus covers the stomach wall with a protective coating. Together with the bicarbonate, this ensures that the stomach wall itself is not damaged by the hydrochloric acid.

Detailed explanation-2: -Second, HCl in the lumen doesnt digest the mucosa because goblet cells in the mucosa secrete large quantities of protective mucus that line the mucosal surface. Basic electrolytes, such as HCO3-, trapped inside the layer of mucus neutralize any HCl that penetrates the mucus.

Detailed explanation-3: -It acts as part of a barrier that protects the stomach wall from the acid and digestive enzymes within the stomach lumen. This barrier is also made up of a bicarbonate secretion and the epithelial cells themselves, which are tightly joined together.

Detailed explanation-4: -The mucus therefore acts as a barrier to prevent pepsin from coming into contact with the proteins that make up the stomach. We have therefore determined that the correct answer is (C). Pepsin does not end up digesting the stomach because the epithelial cells of the stomach secrete a protective mucus layer.

There is 1 question to complete.