NEET PG DENTAL EXAM

Detailed explanation-1: -Tight junctions prevent diffusion of proteins between apical and basolateral domains. Tight junctions not only function to restrict paracellular diffusion of small molecule but they also act as a diffusion barrier in the plasma membrane of epithelial cell to separate the apical and basolateral sides.

Detailed explanation-2: -Tight junctions (TJs), the most apical components of the cell–cell junctional complexes, play a crucial role in the establishment and maintenance of cell polarity within tissues.

Detailed explanation-3: -Types of Cell Junctions Figure 1: The three basic types of cell-to-cell junctions are tight junctions, gap junctions, and anchoring junctions. At one end of the spectrum is the tight junction, which separates the cells into apical and basal compartments.