HISTOLOGY
INTEGUMENTARY SYSTEM SKIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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melanin gets into arteries
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melanosomes surround the nucleus
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melanocytes move to the stratum corneum
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melanocytes absorb melanin
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Detailed explanation-1: -These melanosomes are then taken up by adjacent keratinocytes-the predominant type of skin cell. The melanosomes surround the keratinocyte nuclei, forming a shield that protects DNA from UV radiation. Researchers have known for years that polymers of dopamine act in many situations as an artificial form of melanin.
Detailed explanation-2: -Melanin can form supranuclear caps in human epidermis, suggesting that intracellular melanin reduces ultraviolet transmission to underlying cell nuclei and inhibits the formation of ultraviolet induced DNA photoproducts.
Detailed explanation-3: -Keratinocytes store melanin in membrane-bound compartments and position them into a “helmet” surrounding the nucleus to protect their DNA from ultraviolet radiation (UVR) damage (Wu and Hammer 2014).
Detailed explanation-4: -Melanin pigments protect the skin from DNA damage by surrounding–and thus guarding–the nuclei of keratinocytes.