NEET PG DENTAL EXAM

Detailed explanation-1: -In most cases, Merkel cells complex with somatosensory afferents to form slowly adapting touch receptors; it is unclear, however, whether mechanosensory transduction occurs in the Merkel cell, the somatosensory afferent or both.

Detailed explanation-2: -Merkel cells are usually associated with nerve endings located in the skin and in some parts of the mucosa of all vertebrates. They function as mechanoreceptors and are found in mam-malian epidermis, as well as in the epithelium of ectoderm-derived mucosa [1–3].

Detailed explanation-3: -A special type of cell found right below the epidermis (top layer of skin). These cells are very close to the nerve endings that receive the sensation of touch and may be involved in touch.

Detailed explanation-4: -The Merkel cell–neurite complexes are thought to serve as mechanoreceptors and to be responsible for the sensation of touch via Piezo2-dependent transmission channels. They are clustered near unmyelinated sensory nerve endings, where they group and form ‘touch spots’ at the bottom of rete ridges.